The match between npower League One bottom side Hartlepool and fellow strugglers Portsmouth was called off at 9am
A statement on the Hartlepool website read: "Today's game with Portsmouth has been postponed after referee Darren Bond carried out a second inspection of the Victoria Park pitch.
"Heavy rain throughout the week has left the playing surface extremely wet and more showers this morning caused concern for the match official.
"With forecasts suggesting further heavier rain is on the way later this morning and in to the afternoon - and with the knowledge of visiting fans making a long journey - the referee felt there was no alternative but to call the game off."
The game between Brentford and Stevenage went the same way just before midday.
More than half ot the day's games in League Two have also fallen foul of the wet weather, which has wreaked havoc in the Blue Square Premier too.
North of the border, the Irn-Bru SFL Second Division match between Brechin and Ayr was postponed on Friday.
Racing was also affected, with this afternoon's meeting at Navan cancelled because of a waterlogged track.
Officials at the County Meath circuit were left with no other option following an early-morning course inspection.
Postponed football matches:
npower League 1
Brentford v Stevenage
Hartlepool v Portsmouth
npower League 2
Bristol Rovers v Rotherham
Morecambe v Dagenham & Redbridge
Oxford v Fleetwood
Torquay v Exeter
Wycombe v Bradford
York v Gillingham
Blue Square Bet Premier
AFC Telford v Luton
Alfreton v Barrow
Cambridge Utd v Nuneaton
Ebbsfleet v Hereford
Gateshead v Stockport
Hyde v Mansfield
Newport County v Braintree
Tamworth v Newport
Woking v Forest Green