Aguero, signed for a club-record ?£38million from Atletico Madrid last month, made his City bow when he was introduced as a substitute with around half an hour to go in Monday's game against Swansea at the Etihad Stadium and marked the occasion by scoring twice and providing an assist for David Silva in a crushing 4-0 victory.
"Aguero is only 23 years old, but for six years he has played in a top, senior team in Argentina and Spain," Mancini said. "I think it will be no problem and I am happy that on his debut in the Premier League, he has scored two goals. For a striker, it is very important."
Aguero's compatriot Carlos Tevez could be set to make his first appearance of the season for City when they face Bolton on Sunday.
After a fraught summer, during which the forward handed in an official transfer request and was unsuccessfully pursued by his former club Corinthians, Tevez returned to training with the Blues last week.
Inter Milan have been linked with the 27-year-old, but it appears no further bids have been forthcoming.
He did not feature in the squad for the Swansea match, but Mancini has already made it clear he would be happy for Tevez to stay and will consider him for Sunday.
"He has worked very well in these two weeks," Mancini said.
"When Carlos plays, he always plays very well and gives 100%.
"I think maybe he is not 100% fit, but his mind is okay."
Source: PA
Source: PA