Manchester City v Wigan (1605 GMT)
Manchester City are still without defender Matija Nastasic (knee) and striker Stevan Jovetic (hamstring). Striker Edin Dzeko is in contention despite reports that he was unhappy about playing 90 minutes for Bosnia-Herzegovina in midweek due to a fitness issue. With manager Manuel Pellegrini regularly playing his second-choice goalkeeper in domestic cup ties, there could be another opportunity for Costel Pantilimon.
FA Cup holders Wigan are unlikely to have top scorer Nick Powell back in time from a hamstring problem. Ben Watson, whose late headed goal defeated City at Wembley last May, is out for the season after sustaining a double fracture in his leg while Martyn Waghorn, Ryan Tunnicliffe and Rob Kiernan are all cup-tied. Winger Callum McManaman (ankle) may feature for the first time since the last round. Long-term injury victims Scott Carson (thigh), Gary Caldwell (calf) and Shaun Maloney (hip) are all back in training, although this clash is likely to come too soon for each of them.
Top goalscorers (all competitions): Sergio Aguero (Man City) 26; Nick Powell (Wigan) 10