But with a more attacking approach, Shaun Wright-Phillips is likely to move into attack to partner top scorer Nicolas Anelka, who has scored six times in seven starts against the visitors Blackburn.
That will see City return to a four-man midfield, though the fit-again Claudio Reyna will not be thrust back into the starting line-up just yet.
The American captain has been training all week after being sidelined for two months with a thigh injury.
"It will probably be the same eleven that started against Manchester United," Keegan confirmed on the City website.
He added: "I looked at Claudio in training and thought that he is just the type to give a good half hour to. That is what you want from your substitutes."