The Italian says it important his side focus on their remaining six games and are not distracted.
Tottenham are now two points behind City following the thrilling 3-3 draw against Arsenal.
The clubs are due to meet at Eastlands on May 10 and the result could prove decisive for the second successive year. Tottenham won that encounter thanks to Peter Crouch's late headed winner to progress into the Champions League for the first time.
Mancini is relaxed about the situation.
"It was a good game between Tottenham and Arsenal," he said. "But everything is in our hands. We do not depend on Tottenham or other teams. If we win our games we will go in the Champions League."
Source: PA
Source: PA